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indirect impact to the skull, impact location, mobility of the head, the surface on which the animal is positioned, as well as projectile shape and material ( 2.3 Controlled cortical impact model (CCI) In the CCI model, the brain is impacted via surgically exposed dura by a rapidly accelerated rod with preset computer guided depth of impact (Ma et al., 2019)

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We have determined that the brain angiotensin and HGF/c-Met systems interact in such a way that angiotensin IV (AngIV)-based analogs including Nle1-AngIV, Norleual-AngIV, Dihexa, and others influence HGF dimerization which is a prerequisite to binding at the Met receptor

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